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磷脂酶D作用于磷脂酰肌醇生成双(磷脂酰)肌醇和磷脂酸。

Formation of bis(phosphatidyl)inositol and phosphatidic acid by phospholipase D action on phosphatidylinositol.

作者信息

Clarke N G, Irvine R F, Dawson R M

出版信息

Biochem J. 1981 May 1;195(2):521-3. doi: 10.1042/bj1950521.

DOI:10.1042/bj1950521
PMID:7316969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1162918/
Abstract

Phosphatidylinositol is readily attacked by phospholipase D. Although some phosphatidic acid is produced by hydrolysis, the main products are bis(phosphatidyl)inositols most likely formed by a transphosphatidylation reaction between two substrate molecules.

摘要

磷脂酰肌醇很容易被磷脂酶D攻击。虽然通过水解会产生一些磷脂酸,但主要产物是双(磷脂酰)肌醇,很可能是由两个底物分子之间的转磷脂酰基反应形成的。

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本文引用的文献

1
The distribution of free mesoinositol in mammalian tissues, including some observations on the lactating rat.游离肌醇在哺乳动物组织中的分布,包括对泌乳大鼠的一些观察。
Biochem J. 1961 Mar;78(3):606-10. doi: 10.1042/bj0780606.
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Phosphorus assay in column chromatography.柱色谱法中的磷测定
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Complex lipids of a lipolytic and general-fatty-acid-requiring Butyrivibrio sp. isolated from the ovine rumen.从绵羊瘤胃中分离出的一种需要脂肪分解和一般脂肪酸的丁酸弧菌属的复合脂质。
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Phosphatidylinositol phosphodiesterase in higher plants.高等植物中的磷脂酰肌醇磷酸二酯酶。
Biochem J. 1980 Oct 15;192(1):279-83. doi: 10.1042/bj1920279.
5
The formation of phosphatidylglycerol and other phospholipids by the transferase activity of phospholipase D.通过磷脂酶D的转移酶活性形成磷脂酰甘油和其他磷脂。
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Transphosphatidylation by phospholipase D.磷脂酶D介导的转磷脂酰基作用
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7
Enzymatic formation of cardiolipin from phosphatidylglycerol by the transphosphatidylation mechanism catalyzed by phospholipase D.磷脂酶D催化的转磷脂酰基化机制下由磷脂酰甘油酶促形成心磷脂。
Can J Biochem. 1973 Jun;51(6):747-53. doi: 10.1139/o73-093.
8
The distribution of phospholipase D in developing and mature plants.磷脂酶D在发育中和成熟植物中的分布。
Biochem J. 1969 May;112(5):787-94. doi: 10.1042/bj1120787.
9
Phospholipase D.磷脂酶D
Adv Lipid Res. 1978;16:267-326. doi: 10.1016/b978-0-12-024916-9.50011-1.
10
Inositol cyclis phosphate as a product of phosphatidylinositol breakdown by phospholipase C (Bacillus cereus).
FEBS Lett. 1975 May 15;53(3):302-4. doi: 10.1016/0014-5793(75)80041-x.