磷脂酶D作用于磷脂酰肌醇生成双（磷脂酰）肌醇和磷脂酸。
Formation of bis(phosphatidyl)inositol and phosphatidic acid by phospholipase D action on phosphatidylinositol.
作者信息
Clarke N G, Irvine R F, Dawson R M
出版信息
Biochem J. 1981 May 1;195(2):521-3. doi: 10.1042/bj1950521.
Abstract
Phosphatidylinositol is readily attacked by phospholipase D. Although some phosphatidic acid is produced by hydrolysis, the main products are bis(phosphatidyl)inositols most likely formed by a transphosphatidylation reaction between two substrate molecules.
摘要
磷脂酰肌醇很容易被磷脂酶D攻击。虽然通过水解会产生一些磷脂酸，但主要产物是双（磷脂酰）肌醇，很可能是由两个底物分子之间的转磷脂酰基反应形成的。
相似文献
1
Formation of bis(phosphatidyl)inositol and phosphatidic acid by phospholipase D action on phosphatidylinositol.磷脂酶D作用于磷脂酰肌醇生成双（磷脂酰）肌醇和磷脂酸。
Biochem J. 1981 May 1;195(2):521-3. doi: 10.1042/bj1950521.
2
Phosphatidylinositol hydrolysis by human plasma phospholipase D.
FEBS Lett. 1990 Jan 1;259(2):237-40. doi: 10.1016/0014-5793(90)80017-d.
3
Receptor-mediated signalling pathways acting through hydrolysis of membrane phospholipids in cardiomyocytes.通过心肌细胞中膜磷脂水解起作用的受体介导信号通路。
Cardioscience. 1993 Sep;4(3):121-31.
4
5
A phospholipase D specific for the phosphatidylinositol anchor of cell-surface proteins is abundant in plasma.一种作用于细胞表面蛋白磷脂酰肌醇锚定物的磷脂酶D在血浆中含量丰富。
Proc Natl Acad Sci U S A. 1988 Feb;85(4):980-4. doi: 10.1073/pnas.85.4.980.
6
Epidermal growth factor-induced hydrolysis of phosphatidylcholine by phospholipase D and phospholipase C in human dermal fibroblasts.表皮生长因子诱导人皮肤成纤维细胞中磷脂酶D和磷脂酶C对磷脂酰胆碱的水解作用。
J Cell Physiol. 1991 Feb;146(2):309-17. doi: 10.1002/jcp.1041460216.
7
Relative contribution of phosphoinositides and phosphatidylcholine hydrolysis to the actions of carbamylcholine, thyrotropin (TSH), and phorbol esters on dog thyroid slices: regulation of cytidine monophosphate-phosphatidic acid accumulation and phospholipase-D activity. I. Actions of carbamylcholine, calcium ionophores, and TSH.磷酸肌醇和磷脂酰胆碱水解对氨甲酰胆碱、促甲状腺素（TSH）及佛波酯作用于犬甲状腺切片的相对贡献：胞苷一磷酸 - 磷脂酸积累和磷脂酶 - D活性的调节。I. 氨甲酰胆碱、钙离子载体及TSH的作用
Endocrinology. 1994 Dec;135(6):2488-96. doi: 10.1210/endo.135.6.7988436.
8
THE POSITIONAL DISTRIBUTION OF THE FATTY ACIDS IN PHOSPHATIDYL INOSITOL.磷脂酰肌醇中脂肪酸的位置分布
Biochim Biophys Acta. 1964 Aug 5;84:458-60. doi: 10.1016/0926-6542(64)90010-1.
9
Synthesis of 5'-phosphatidylnucleosides by phospholipase D-catalyzed transphosphatidylation.磷脂酶D催化的转磷脂酰基反应合成5'-磷脂酰核苷
Nucleic Acids Symp Ser. 1986(17):73-6.
10
The functions of phospholipases and their hydrolysis products in plant growth, development and stress responses.磷脂酶的功能及其水解产物在植物生长、发育和胁迫响应中的作用。
Prog Lipid Res. 2022 Apr;86:101158. doi: 10.1016/j.plipres.2022.101158. Epub 2022 Feb 5.
引用本文的文献
1
The transphosphatidylation activity of phospholipase D.磷脂酶D的转磷脂酰基活性
Mol Cell Biochem. 1996;157(1-2):101-5. doi: 10.1007/BF00227886.
2
Rapid attenuation of receptor-induced diacylglycerol and phosphatidic acid by phospholipase D-mediated transphosphatidylation: formation of bisphosphatidic acid.磷脂酶D介导的转磷脂酰基作用使受体诱导的二酰基甘油和磷脂酸快速衰减：双磷脂酸的形成。
EMBO J. 1993 Jul;12(7):2655-62. doi: 10.1002/j.1460-2075.1993.tb05926.x.
3
The regulation and cellular functions of phosphatidylcholine hydrolysis.磷脂酰胆碱水解的调节及其细胞功能
Biochem J. 1990 Jul 15;269(2):281-91. doi: 10.1042/bj2690281.
本文引用的文献
1
The distribution of free mesoinositol in mammalian tissues, including some observations on the lactating rat.游离肌醇在哺乳动物组织中的分布，包括对泌乳大鼠的一些观察。
Biochem J. 1961 Mar;78(3):606-10. doi: 10.1042/bj0780606.
2
Phosphorus assay in column chromatography.柱色谱法中的磷测定
J Biol Chem. 1959 Mar;234(3):466-8.
3
Complex lipids of a lipolytic and general-fatty-acid-requiring Butyrivibrio sp. isolated from the ovine rumen.从绵羊瘤胃中分离出的一种需要脂肪分解和一般脂肪酸的丁酸弧菌属的复合脂质。
Biochem J. 1980 Nov 1;191(2):555-60. doi: 10.1042/bj1910555.
4
Phosphatidylinositol phosphodiesterase in higher plants.高等植物中的磷脂酰肌醇磷酸二酯酶。
Biochem J. 1980 Oct 15;192(1):279-83. doi: 10.1042/bj1920279.
5
The formation of phosphatidylglycerol and other phospholipids by the transferase activity of phospholipase D.通过磷脂酶D的转移酶活性形成磷脂酰甘油和其他磷脂。
Biochem J. 1967 Jan;102(1):205-10. doi: 10.1042/bj1020205.
6
Transphosphatidylation by phospholipase D.磷脂酶D介导的转磷脂酰基作用
J Biol Chem. 1967 Feb 10;242(3):477-84.
7
Enzymatic formation of cardiolipin from phosphatidylglycerol by the transphosphatidylation mechanism catalyzed by phospholipase D.磷脂酶D催化的转磷脂酰基化机制下由磷脂酰甘油酶促形成心磷脂。
Can J Biochem. 1973 Jun;51(6):747-53. doi: 10.1139/o73-093.
8
The distribution of phospholipase D in developing and mature plants.磷脂酶D在发育中和成熟植物中的分布。
Biochem J. 1969 May;112(5):787-94. doi: 10.1042/bj1120787.
9
Phospholipase D.磷脂酶D
Adv Lipid Res. 1978;16:267-326. doi: 10.1016/b978-0-12-024916-9.50011-1.
10
Inositol cyclis phosphate as a product of phosphatidylinositol breakdown by phospholipase C (Bacillus cereus).
FEBS Lett. 1975 May 15;53(3):302-4. doi: 10.1016/0014-5793(75)80041-x.
Zotero 插件