Sokolov V E, Shabadash S A, Zelikina T I
Biol Bull Acad Sci USSR. 1980 Sep-Oct;7(5):331-46.
In recent years it has been shown on the example of primate skin that in addition to abundant cholinergic innervation, the eccrine glands are also supplied by adrenergic fibers, containing catecholamines. The presence of an adrenergic component of the innervation is demonstrated on the plantar eccrine sweat glands of a number of rodents and the cat by the detection of monoamine oxidase in it. The myelin nerve trunks, the short unmyelinated varicose terminals in direct contact with the secretory cells, as well as the mitochondria of cells of the eccrine sweat glands are rich in monoamine oxidase. Specific and nonspecific cholinesterases are localized in the dense network of nerves in lacing the secretory portions of the glands; individual fibers accompany the excretory ducts. The acetylcholinesterase concentration is lower than the concentration of nonspecific cholinesterase. In rats with chemical sympathectomy, induced by four-week administration of 25 mg/kg guanethidine from the first day of birth, in which 99% of the neurons in the stellate ganglia die, the monoamine oxidase concentration in the myelin nerves and in the mitochondria of the secretory cells drops very sharply, and acetylcholinesterase disappears from the nerves surrounding the glands.
近年来，以灵长类动物皮肤为例表明，除了丰富的胆碱能神经支配外，外分泌腺还由含有儿茶酚胺的肾上腺素能纤维供应。通过检测其中的单胺氧化酶，在一些啮齿动物和猫的足底外分泌汗腺中证实了神经支配中存在肾上腺素能成分。有髓神经干、与分泌细胞直接接触的短无髓曲张终末以及外分泌汗腺细胞的线粒体富含单胺氧化酶。特异性和非特异性胆碱酯酶定位于围绕腺体分泌部的致密神经网中；个别纤维伴随排泄管。乙酰胆碱酯酶的浓度低于非特异性胆碱酯酶的浓度。在从出生第一天起连续四周给予25mg/kg胍乙啶诱导化学性交感神经切除术的大鼠中，星状神经节中99%的神经元死亡，有髓神经和分泌细胞线粒体中的单胺氧化酶浓度急剧下降，乙酰胆碱酯酶从腺体周围的神经中消失。
