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[氯贝丁酯诱导大鼠肝细胞质中低分子量多肽含量的变化]

[Clofibrate-induced changes in the content of a low molecular-weight polypeptide in rat liver cell cytoplasm].

作者信息

Antonenkov V D, Pirozhkov S V, Sal'nikov Ia A, Panchenko L F

出版信息

Biokhimiia. 1981 Dec;46(12):2208-14.

PMID:7317540
Abstract

Data from Na-DS polyacrylamide gel electrophoresis suggest that the relative amount of the polypeptide with molecular weight of 12,000 in the soluble fraction of rat liver cytosol is increased after treatment with the hypolipidemic agent clofibrate. The experimental results indicate that this polypeptide is identical to a fatty acid binding protein (Z-protein).

摘要

来自钠-十二烷基硫酸钠聚丙烯酰胺凝胶电泳的数据表明,用降血脂药物氯贝丁酯处理后,大鼠肝细胞溶胶可溶性部分中分子量为12,000的多肽相对含量增加。实验结果表明,该多肽与一种脂肪酸结合蛋白(Z蛋白)相同。

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Biokhimiia. 1981 Dec;46(12):2208-14.
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