Chou K C
Can J Biochem. 1981 Sep;59(9):757-61. doi: 10.1139/o81-105.
A new graphical rule is presented for deriving the rate equations of enzyme reactions. The new rule has the following advantages: (i) it is very effective in simplifying the calculations for complex mechanisms, especially for those with branched pathways; (ii) a significant and intuitive correlation between the rule and the mechanism is established through the product-releasing cycle and product-combining cycle.
提出了一种用于推导酶反应速率方程的新图形规则。新规则具有以下优点:(i) 在简化复杂机制的计算方面非常有效,特别是对于具有分支途径的机制;(ii) 通过产物释放循环和产物结合循环在该规则与机制之间建立了显著且直观的相关性。