文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Goto A, Ikeda T, Tobian L, Iwai J, Johnson M A

Clin Sci (Lond). 1981 Dec;61 Suppl 7:53s-55s. doi: 10.1042/cs061053s.

The rise in blood pressure in Dahl salt-sensitive rats that received intracerebroventricular 6-hydroxydopamine was almost half that of the control rats throughout 20 weeks of high (8%) NaCl feeding. 2. The rise in blood pressure in Dahl salt-sensitive rats with bilateral complete electrolytic lesions of the paraventricular nuclei was almost half that of the control rats during 12 weeks of high (8%) NaCl feeding. 3. The bilateral complete electrolytic lesions of the suprachiasmatic nuclei enhanced the development of NaCl hypertension in Dahl salt-sensitive rats. 4. These results show that NaCl-induced hypertension in Dahl salt-sensitive rats requires the integrity of the central nervous system catecholaminergic neurones and the paraventricular nuclei for its full expression.

在高盐（8%）喂养的20周内，接受脑室内注射6-羟基多巴胺的 Dahl 盐敏感大鼠的血压升高幅度几乎是对照大鼠的一半。2. 在高盐（8%）喂养的12周内，双侧室旁核完全电解损伤的 Dahl 盐敏感大鼠的血压升高幅度几乎是对照大鼠的一半。3. 视交叉上核的双侧完全电解损伤增强了 Dahl 盐敏感大鼠的盐性高血压发展。4. 这些结果表明，Dahl 盐敏感大鼠中由氯化钠诱导的高血压充分表现需要中枢神经系统儿茶酚胺能神经元和室旁核的完整性。

Goto A, Ikeda T, Tobian L, Iwai J, Johnson M A

Clin Sci (Lond). 1981 Dec;61 Suppl 7:53s-55s. doi: 10.1042/cs061053s.

The rise in blood pressure in Dahl salt-sensitive rats that received intracerebroventricular 6-hydroxydopamine was almost half that of the control rats throughout 20 weeks of high (8%) NaCl feeding. 2. The rise in blood pressure in Dahl salt-sensitive rats with bilateral complete electrolytic lesions of the paraventricular nuclei was almost half that of the control rats during 12 weeks of high (8%) NaCl feeding. 3. The bilateral complete electrolytic lesions of the suprachiasmatic nuclei enhanced the development of NaCl hypertension in Dahl salt-sensitive rats. 4. These results show that NaCl-induced hypertension in Dahl salt-sensitive rats requires the integrity of the central nervous system catecholaminergic neurones and the paraventricular nuclei for its full expression.

在高盐（8%）喂养的20周内，接受脑室内注射6-羟基多巴胺的 Dahl 盐敏感大鼠的血压升高幅度几乎是对照大鼠的一半。2. 在高盐（8%）喂养的12周内，双侧室旁核完全电解损伤的 Dahl 盐敏感大鼠的血压升高幅度几乎是对照大鼠的一半。3. 视交叉上核的双侧完全电解损伤增强了 Dahl 盐敏感大鼠的盐性高血压发展。4. 这些结果表明，Dahl 盐敏感大鼠中由氯化钠诱导的高血压充分表现需要中枢神经系统儿茶酚胺能神经元和室旁核的完整性。