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胃十二指肠克罗恩病的诊断与治疗方面

[Diagnostic and therapeutic aspects of gastroduodenal Crohn disease].

作者信息

Merkle P, Heil T, Herfarth C

出版信息

Chirurg. 1981 Dec;52(12):758-62.

PMID:7318570
Abstract

The duodenum or the stomach were involved in 20 (11%) of 177 patients with Crohn's disease. Four patients had no symptoms in the upper gastrointestinal tract, in ten patients pains and gastric disorders recurred. Six patients had severe symptoms caused by stenosis of the stomach or duodenum. The endoscopical and histological findings correlated to the severity of the symptoms. Early pathological changes were identified only by gastroscopy. We have little experience of the medical treatment of Crohn's disease of the duodenum or the stomach. A bypass procedure (gastrojejunostomy combined wih proximal-gastric vagotomy (PGV)) is indicated in all cases of severe gastric or duodenal stenosis.

摘要

177例克罗恩病患者中,十二指肠或胃受累的有20例(11%)。4例患者上消化道无症状,10例患者疼痛和胃部不适复发。6例患者因胃或十二指肠狭窄出现严重症状。内镜和组织学检查结果与症状严重程度相关。早期病理改变仅通过胃镜检查发现。我们对十二指肠或胃克罗恩病的药物治疗经验很少。对于所有严重胃或十二指肠狭窄病例,均需行旁路手术(胃空肠吻合术联合近端胃迷走神经切断术(PGV))。

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