Yamori Y, Nara Y, Horie R, Ohtaka M, Ohta K, Mitani F
Jpn Heart J. 1978 Jul;19(4):597-8. doi: 10.1536/ihj.19.597.
Biomembrane characteristics in stroke-prone SHR (SHRSP) and stroke-resistant SHR (SHRSR) were examined using erythrocytes as a simplified model. When erythrocytes were exposed to osmotic stress in the process of the migration from a higher to a lower osmotic gradient by the coil planet centrifugation, erythrocytes from SHRSP were hemolyzed at a higher osmotic pressure than those from SHRSR. Such a difference in biomembrane characteristics may be useful for detecting a genetic disposition of stroke.
