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患有呼吸问题的新生儿抗利尿激素分泌异常综合征

Syndrome of inappropriate antidiuretic hormone secretion in newborn infants with respiratory problems.

作者信息

Nutman J, Wilunsky E, Avni A, Reisner S H

出版信息

Isr J Med Sci. 1981 Nov;17(11):1009-13.

PMID:7319787
Abstract

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) has not often been described in newborn infants. Of 61 infants with respiratory problems who were admitted to our neonatal intensive care unit over a six-month period from July 1978, three had SIADH, diagnosed on the basis of hyponatremia, weight gain and the excretion of highly concentrated urine. In one infant the onset of marked hyponatremia was very rapid and resulted in deep coma. The occurrence of this syndrome in 5% of infants under intensive care for neonatal respiratory problems makes it essential to monitor these infants closely for deviations in fluid and electrolyte balance.

摘要

抗利尿激素分泌不当综合征(SIADH)在新生儿中并不常见。在1978年7月起的六个月期间,入住我们新生儿重症监护病房的61名患有呼吸问题的婴儿中,有三名患有SIADH,根据低钠血症、体重增加和高浓度尿液排泄进行诊断。在一名婴儿中,明显低钠血症的发作非常迅速,导致深度昏迷。在接受新生儿呼吸问题重症监护的婴儿中,该综合征的发生率为5%,这使得密切监测这些婴儿的液体和电解质平衡偏差至关重要。

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