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二尖瓣狭窄患者左心室形态及收缩功能异常:一项横断面超声心动图研究(作者译)

[Abnormal left ventricular configuration and contraction in patients with mitral stenosis: a cross-sectional echocardiographic study (author's transl)].

作者信息

Yoshida K, Yoshikawa J, Yanagihara K, Kato H, Takagi Y, Okumachi F

出版信息

J Cardiogr. 1981 Sep;11(3):693-701.

PMID:7320548
Abstract

To assess left ventricular shape and contraction pattern under the condition of the narrowed mitral orifice, 41 patients with mitral stenosis were studied by cross-sectional and M-mode echocardiography. Abnormal left ventricular configuration and asynergy were observed in 23 patients (56%). The change in configuration persisted during the cardiac cycle and was mainly due to a straightening and abnormal motion of the interventricular septum. Furthermore, hypokinesis or akinesis of the posterior left ventricular wall contributed to the change of left ventricular shape. Consequently the left ventricular shape became from circular to half moon- or pear-like configuration. Of these 23 patients, 19 had a severe degree of subvalvular lesion, whereas such a lesion was noted in only 6 of the 18 patients with normal left ventricular shape and contraction pattern. It is considered that a rigid mitral complex immobilizes the posterior wall of the left ventricle in patients with mitral stenosis. In addition, tricuspid regurgitation, which was frequently observed in our patients, may play an important role in abnormal septal motion. This study showed that abnormal left ventricular shape and asynergy in the posterior wall are not rare in patients with mitral stenosis and are due to a rigid mitral complex and associated tricuspid regurgitation.

摘要

为评估二尖瓣口狭窄情况下左心室的形态和收缩模式,对41例二尖瓣狭窄患者进行了横断面和M型超声心动图研究。23例患者(56%)观察到左心室形态异常和运动失调。形态变化在心动周期中持续存在,主要是由于室间隔变直和异常运动。此外,左心室后壁运动减弱或消失也导致了左心室形态的改变。结果,左心室形态从圆形变为半月形或梨形。在这23例患者中,19例有严重程度的瓣下病变,而在18例左心室形态和收缩模式正常的患者中,只有6例有此类病变。认为二尖瓣复合体僵硬使二尖瓣狭窄患者的左心室后壁固定。此外,在我们的患者中经常观察到的三尖瓣反流可能在室间隔异常运动中起重要作用。本研究表明,二尖瓣狭窄患者左心室形态异常和后壁运动失调并不少见,是由于二尖瓣复合体僵硬和相关的三尖瓣反流所致。

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