Dany F, Liozon F, Adenis J P, Michel J P, Vidal E, Kim M
J Mal Vasc. 1981;6(4):273-7.
Nine patients with histologically confirmed Horton's diseases were explored by Doppler ultrasound examination, before and after corticotherapy, of the cervical arteries, temporal arteries (N = 9), and branches of the ophthalmic artery: internal nasal (N = 9), central retinal, and supraorbital (N = 6). Excellent correlations existed between histological findings and results of Doppler examination, concerning the severity of the lesions (80% correlation). Circulatory slowing was evident in the ophthalmic vessels studied, with alterations in the shape of peak velocities in 6 of the 9 cases. Major abnormalities were present in 3 patients; two of them presenting transient or permanent amaurosis. Doppler curves improved after corticotherapy, their shape and amplitude becoming equivalent to those of a control population of the same age. Doppler examinations appear to be of diagnostic value in Horton's disease, as well as being able to predict the risk of ophthalmological complications; more effective surveillance of corticotherapy is possible.
对9例经组织学确诊为 Horton 病的患者,在进行皮质激素治疗前后,用多普勒超声检查了颈总动脉、颞浅动脉(n = 9)以及眼动脉分支:鼻内动脉(n = 9)、视网膜中央动脉和眶上动脉(n = 6)。在病变严重程度方面,组织学检查结果与多普勒检查结果之间存在极好的相关性(相关性为80%)。在所研究的眼血管中,循环减慢明显,9例中有6例峰值速度形态发生改变。3例患者存在严重异常;其中2例出现短暂性或永久性黑矇。皮质激素治疗后多普勒曲线有所改善,其形态和幅度与同年龄对照组相当。多普勒检查在 Horton 病中似乎具有诊断价值,并且能够预测眼科并发症的风险;对皮质激素治疗进行更有效的监测成为可能。