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[动脉多普勒在霍顿病中的意义。59例病例报告的前瞻性研究]

[Significance of arterial Doppler in Horton's disease. Prospective study of 59 case reports].

作者信息

Vinckier L, Hatron P Y, Gadenne C, Catteau M H, Gosset D, Devulder B

机构信息

Service de Médecine interne, Clinique médicale A, CHU Hôpital Cl. Huriez, Lille.

出版信息

J Mal Vasc. 1989;14 Suppl C:116-22.

PMID:2696768
Abstract

Several preliminary studies drew attention to the value of Doppler examination in temporal arteritis. This study involving 59 cases aimed to define the value of Doppler examination in the diagnosis of the disease, evaluation of ophthalmic risk and in the monitoring of treatment. The study involved 59 patients and 47 controls with no evidence of temporal arteritis, but of comparable mean age. The following arteries were investigated before treatment: arteries of limbs, subclavian, vertebral, carotid, temporal, occipital, facial and ophthalmic recorded via the internal nasal branch and also transocularly. The results were expressed in the form of a score from 0 to 3 describing the degree of deterioration of the curves. A mean score corresponding to the mean of the scores of the cephalic arteries was calculated for each patient and each control. The specificity and sensitivity of the investigation were studied, based on this mean score by ROC analysis. The progression under treatment was monitored for more than 24 months in 20 patients divided into 3 groups: group I: 6 patients cured; group II: 6 patients with late recurrence of temporal arteritis after steroid withdrawal; group III: 8 patients with progressive disease. 81.5% of temporal arteries were pathological, including 60% with tight stenosis (score 2 and 3). Morphological anomalies in the curves were also noted at the level of the occipital arteries (69%), facial arteries (80%), as well as the ophthalmic artery at both recording sites (internal nasal: 84.5%, transocular: (73%) (table I).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

几项初步研究使人们注意到多普勒检查在颞动脉炎中的价值。这项涉及59例患者的研究旨在明确多普勒检查在该疾病诊断、眼科风险评估及治疗监测中的价值。该研究纳入了59例患者和47例对照,这些对照无颞动脉炎证据,但平均年龄相当。在治疗前对以下动脉进行了检查:通过鼻内分支以及经眼记录四肢动脉、锁骨下动脉、椎动脉、颈动脉、颞动脉、枕动脉、面动脉和眼动脉。结果以0至3分的评分形式表示,描述曲线的恶化程度。为每位患者和每位对照计算对应头部动脉评分均值的平均得分。基于该平均得分,通过ROC分析研究了该检查的特异性和敏感性。对20例患者进行了超过24个月的治疗过程监测,这些患者分为3组:第一组:6例治愈;第二组:6例在停用类固醇后出现颞动脉炎晚期复发;第三组:8例病情进展。81.5%的颞动脉呈病理性,其中60%为严重狭窄(评分为2分和3分)。在枕动脉(69%)、面动脉(80%)以及两个记录部位的眼动脉(鼻内:84.5%,经眼:73%)水平也观察到曲线形态异常(表I)。(摘要截取自250字)

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