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Regional changes in the binding of [3H] concanavalin A to mouse blastocysts at implantation: an autoradiographic study.

作者信息

Carollo J R, Weitlauf H M

出版信息

J Exp Zool. 1981 Nov;218(2):247-51. doi: 10.1002/jez.1402180217.

DOI:10.1002/jez.1402180217
PMID:7320689
Abstract

Implanting and delayed-implanting mouse blastocysts were incubated in vitro with [3H] concanavalin A (Con A), and the distribution of binding on their surfaces was determined by light microscopic autoradiography. The density of binding was uniform on the trophectoderm of delayed-implanting embryos and was not changed on the polar surface of implanting embryos. However, binding was reduced on the proximal mural and distal mural trophectoderm of implanting blastocysts by 36% and 60%, respectively. These results suggest that there is a regional reduction in the density of mannose-like sugars on the surface of mouse blastocysts at the time of attachment and implantation.

摘要

相似文献

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A mannose-binding glycoprotein found in the 4 day post coital rat uterus is involved in pregnancy.在交配后4天的大鼠子宫中发现的一种甘露糖结合糖蛋白与妊娠有关。
Mol Cell Biochem. 1999 May;195(1-2):65-75. doi: 10.1023/a:1006901206170.
2
Carbohydrate-binding profile of a pregnancy-associated rat uterine glycoprotein.
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Radioiodinated surface proteins of rabbit trophectoderm cells.兔滋养外胚层细胞的放射性碘化表面蛋白
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