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n 组分非崩解球体溶解速率的通用模型。

General model for dissolution rates of n-component, nondisintegrating spheres.

作者信息

Carmichael G R, Shah S A, Parrott E L

出版信息

J Pharm Sci. 1981 Dec;70(12):1331-8. doi: 10.1002/jps.2600701211.

Abstract

The dissolution rates of compressed spheres consisting of two and three components were measured. A general model for dissolution rates of n-component, nondisintegrating spheres is discussed. Experimental cases are presented to support the model for two- and three-component spheres, two-component interacting spheres, and three-component spheres containing two components that complex.

摘要

对由两种和三种成分组成的压制球体的溶解速率进行了测定。讨论了n组分、不崩解球体溶解速率的通用模型。给出了实验案例,以支持针对两种和三种成分球体、两种成分相互作用球体以及含有两种发生络合成分的三种成分球体的模型。

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