大鼠髓袢短袢对葡萄糖的转运
Glucose transport by short loops of Henle in the rat.
作者信息
Bishop J H, Green R, Thomas S
出版信息
J Physiol. 1981 Nov;320:127-38. doi: 10.1113/jphysiol.1981.sp013939.
Abstract
- Short loops of Henle were artificially perfused with saline solutions containing 5 or 0 mM-glucose in the presence and absence of phlorizin. 2. Net fluid reabsorption was greater when glucose but no phlorizin was present than in all other series. 3. Glucose was reabsorbed from glucose-containing perfusate and this was abolished by phlorizin. Secretion of glucose occurred into the perfusate which initially contained no glucose and this secretion was enhanced by phlorizin. 4. Sodium reabsorption was inhibited by phlorizin, when glucose was present, but enhanced by phlorizin when glucose was absent. 5. It can be shown that there is secretion of some osmotically active solute in all series. Its secretion is enhanced by phlorizin in the absence of glucose.
摘要
- 在存在和不存在根皮苷的情况下，用含有5或0 mM葡萄糖的盐溶液对短袢髓袢进行人工灌注。2. 当存在葡萄糖但不存在根皮苷时，净液体重吸收比所有其他组都更大。3. 葡萄糖从含葡萄糖的灌注液中被重吸收，而这被根皮苷消除。葡萄糖分泌到最初不含葡萄糖的灌注液中，并且这种分泌被根皮苷增强。4. 当存在葡萄糖时，根皮苷抑制钠重吸收，但当不存在葡萄糖时，根皮苷增强钠重吸收。5. 可以证明，在所有组中都存在某种渗透活性溶质的分泌。在不存在葡萄糖的情况下，根皮苷会增强其分泌。
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