Fleming H A, Bailey S M
J R Coll Physicians Lond. 1981 Oct;15(4):245-6, 249-53.
Myocardial sarcoidosis is not a rare disease in the UK and it is still probably under-diagnosed. A high index of suspicion in necessary for diagnosis of myocardial sarcoidosis, which should be thought of in any unusual form of heart disease for which there is no adequate explanation, particularly if there are serious rhythm changes or unexplained heart failure. Mitral systolic murmurs occur frequently. Histological proof of the aetiology should be sought. The heart is frequently massively involved when other organs have little involvement. Most of these patients present with cardiac symptoms or signs and the high incidence of sudden death is disturbing. The high rate of occurrence in East Anglia is noted, and merits further study. Treatment should be energetic where indicated--but its effects are difficult to assess. This study, representing the largest single source of information on this topic, continues in the hope of shedding more light on a sinister disease.
在英国，心肌结节病并非罕见疾病，可能仍存在诊断不足的情况。诊断心肌结节病需要高度的怀疑指数，对于任何没有充分解释的不寻常形式的心脏病，尤其是出现严重节律变化或不明原因的心力衰竭时，都应考虑到该病。二尖瓣收缩期杂音频繁出现。应寻求病因的组织学证据。当其他器官受累较轻时，心脏常常受到严重累及。这些患者大多表现出心脏症状或体征，猝死的高发生率令人不安。注意到东安格利亚地区该病的高发病率，值得进一步研究。在有指征的情况下应积极治疗——但其效果难以评估。这项研究是关于该主题最大的单一信息来源，仍在继续，希望能更深入地了解这种严重疾病。
