Cameron H U
J R Soc Med. 1981 Dec;74(12):887-91. doi: 10.1177/014107688107401206.
The introduction of microporous metallic implants into which bone can grow to stabilize the implant has necessitated considerable work prior to clinical studies. Ten years of bench and animal testing have resulted in a clinically available prosthesis with a multilayer porous coating with a pore size of 50-300 mu. Initial clinical trials with a 50-100 mu hip prosthesis indicated the necessity to increase the pore size to 300 mu and clinical studies of such prostheses are at present underway.
可使骨组织长入以稳定植入物的微孔金属植入物的引入,在临床研究之前需要进行大量工作。十年的实验台和动物试验已产生了一种临床可用的假体,其具有孔径为50 - 300微米的多层多孔涂层。对孔径为50 - 100微米的髋关节假体进行的初步临床试验表明有必要将孔径增加到300微米,目前正在对此类假体进行临床研究。