Thakur C P, Kumar M, Pathak P K
J Trop Med Hyg. 1981 Dec;84(6):271-6.
Six hundred and ninety-two cases of kala-azar were studied, all confirmed cases. Vaishali, Muzaffarpur, Samsatipur and Sitamarhi were the most affected districts of Bihar. Fever, weight loss, hepatosplenomegaly, anaemia, leucopenia and monocytes were the most commonly found features, whereas pigmentation of skin was found in only 4.48% of cases. Lymphadenopathy and voracious appetite were conspicious by their absence. Study of the incubation period of the disease showed that it may be as short as 24 h. Bone marrow study revealed hypoplastic marrow with increase in the cells of the monocytic series. Serum electrophoresis revealed reduction in albumin and rise in globulin, leading to decrease in A : G ratio. Tuberculin test was negative in the majority of the patients.
对692例黑热病病例进行了研究，均为确诊病例。比哈尔邦受影响最严重的地区是瓦伊沙利、穆扎法尔布尔、萨姆萨特布尔和锡塔马尔希。发热、体重减轻、肝脾肿大、贫血、白细胞减少和单核细胞增多是最常见的症状，而仅有4.48%的病例出现皮肤色素沉着。未发现淋巴结病和食欲亢进。对该病潜伏期的研究表明，其可能短至24小时。骨髓研究显示骨髓发育不全，单核细胞系列细胞增多。血清电泳显示白蛋白降低，球蛋白升高，导致A:G比值降低。大多数患者结核菌素试验呈阴性。
