Szabó G, Takács L, Kovács A, Skalitzki J
Rev Stomatol Chir Maxillofac. 1977;78(5):357-62.
Chemotherapy based upon cellular synchronisation via intra-arterial infusion was used in the treatment of 21 carcinomas of the maxillo-facial region. These tumours had never been treated either by surgery, nor by irradiation. This pre-operative treatment was not aimed at altering ghe indication for the type of operation decided upon at the outset. It was found that a combination of Vincristine, Bleomycine, Methotrexate and Dibromdulcide was more satisfactory than other types of chemotherapy. The most important complication of the method was a thrombosis of the common carotid.
通过动脉内灌注进行细胞同步化的化疗被用于治疗21例颌面部癌。这些肿瘤此前从未接受过手术或放疗。这种术前治疗并非旨在改变最初确定的手术类型的适应证。结果发现,长春新碱、博来霉素、甲氨蝶呤和二溴卫矛醇的联合使用比其他类型的化疗更令人满意。该方法最重要的并发症是颈总动脉血栓形成。