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[基于细胞同步化的多药化疗经验,通过动脉内输注。颌面肿瘤的术前治疗]

[Experience with polychemotherapy based on cell synchronization, via intra-arterial infusions. Preoperative treatment of maxillofacial tumors].

作者信息

Szabó G, Takács L, Kovács A, Skalitzki J

出版信息

Rev Stomatol Chir Maxillofac. 1977;78(5):357-62.

PMID:73213
Abstract

Chemotherapy based upon cellular synchronisation via intra-arterial infusion was used in the treatment of 21 carcinomas of the maxillo-facial region. These tumours had never been treated either by surgery, nor by irradiation. This pre-operative treatment was not aimed at altering ghe indication for the type of operation decided upon at the outset. It was found that a combination of Vincristine, Bleomycine, Methotrexate and Dibromdulcide was more satisfactory than other types of chemotherapy. The most important complication of the method was a thrombosis of the common carotid.

摘要

通过动脉内灌注进行细胞同步化的化疗被用于治疗21例颌面部癌。这些肿瘤此前从未接受过手术或放疗。这种术前治疗并非旨在改变最初确定的手术类型的适应证。结果发现,长春新碱、博来霉素、甲氨蝶呤和二溴卫矛醇的联合使用比其他类型的化疗更令人满意。该方法最重要的并发症是颈总动脉血栓形成。

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