Yamashita M
Nihon Heikatsukin Gakkai Zasshi. 1980 Dec;16(4):315-29.
In dogs anesthetized by pentobarbital sodium, bipolar stimulating and recording electrodes were implanted on the gastric serosal surface and pacing effect of stimuli of rectangular current on the basic electric rhythm (BER) was examined. For judgement of pacing, the appearance of a compensatory pause after off-stimulation was a useful criterion. When BER was recorded at the oral side of stimulation, antiperistaltic one was added. Maximum driven frequency (MDF) was 6.0 +/- 0.6 (SD) cycles/min. The relation between stimulus interval (x) and BER interval (y) was represented by y = x in the stimuli below MDF. In the stimulus frequency until 2 times of MDF above MDF, it was replaced by y = 2x. Phase lag between BERs of two separated points was increased as the stimulus frequency was increased up to MDF. This tendency was observed similarly within 2 times of MDF above MDF. Using a gastrointestinal fiberscope, electric stimulation was delivered from the gastric mucosal side, while BER was recorded from the serosal side in 5 dogs and was recorded with electrodes through the endoscope in 2 dogs. Pacing was possible, too. These results may indicate that pacing and recording of the BER using gastrointestinal fiberscope are applicable clinically.
在戊巴比妥钠麻醉的犬中，将双极刺激和记录电极植入胃浆膜表面，检测矩形电流刺激对基本电节律（BER）的起搏作用。对于起搏的判断，刺激停止后出现代偿性间歇是一个有用的标准。当在刺激的口侧记录BER时，会出现逆蠕动波。最大驱动频率（MDF）为6.0±0.6（标准差）次/分钟。在低于MDF的刺激中，刺激间隔（x）与BER间隔（y）的关系用y = x表示。在高于MDF直至2倍MDF的刺激频率下，该关系变为y = 2x。随着刺激频率增加至MDF，两个分开点的BER之间的相位滞后增加。在高于MDF直至2倍MDF的范围内也观察到类似趋势。在5只犬中，使用胃肠纤维内镜从胃黏膜侧进行电刺激，同时从浆膜侧记录BER，在2只犬中通过内镜用电极记录BER。起搏也是可行的。这些结果可能表明使用胃肠纤维内镜对BER进行起搏和记录在临床上是可行的。
