Takeuchi H, Kondoh I, Kohno M
J Neurosci Methods. 1981 Dec;4(4):365-72. doi: 10.1016/0165-0270(81)90006-6.
An automatic voltage adjuster was designed in order to apply an intracellular rectangular pulse of current and record the membrane potential simultaneously using a single intracellular microelectrode. The original voltage record consists of a rectangular signal signal (Va) due to the resistance of the microelectrode and a slowly rising signal (Vb) which is the proper value of the membrane potential shift produced by the application of the intracellular rectangular pulse of current. The instrument described in this paper samples the original signal (Va + Vb) at 0.5 approximately 1.0 ms after the application of the rectangular pulse of current, holds this voltage level (Va) and subtracts it from the original signal (Va + Vb) to obtain (Vb).
设计了一种自动电压调节器，以便使用单个细胞内微电极施加细胞内矩形电流脉冲并同时记录膜电位。原始电压记录包括由于微电极电阻产生的矩形信号（Va）和一个缓慢上升的信号（Vb），该信号是施加细胞内矩形电流脉冲所产生的膜电位偏移的正确值。本文所述仪器在施加矩形电流脉冲后约0.5至1.0毫秒对原始信号（Va + Vb）进行采样，保持该电压电平（Va）并从原始信号（Va + Vb）中减去它以获得（Vb）。
