Bourgeois C A, Raynaud N, Diatloff-Zito C, Macieira-Coehlo A
Mech Ageing Dev. 1981 Nov;17(3):225-35. doi: 10.1016/0047-6374(81)90060-9.
Human embryonic and adult cells were irradiated with fractionated doses of low dose rate ionizing radiation starting early during their lifespan. Adult cells were found to be more sensitive than fetal cells to ionizing radiation in terms of the number of cells produced during the lifespan of the control and the irradiated cultures. Phase-III adult control cells had fewer chromosomal aberrations than phase-III embryonic control cells. After irradiation there was an increase in chromosomal aberrations in adult cells but no increase in embryonic cells beyond those found in the control cultures. It is suggested that cells that have a higher potential for chromosomal rearrangements survive better after low dose rate ionizing radiation.
在人类胚胎细胞和成年细胞生命早期开始，用低剂量率分次电离辐射进行照射。就对照培养物和受照培养物寿命期间产生的细胞数量而言，发现成年细胞比胎儿细胞对电离辐射更敏感。III期成年对照细胞的染色体畸变比III期胚胎对照细胞少。照射后，成年细胞中的染色体畸变增加，但胚胎细胞中的染色体畸变除了在对照培养物中发现的那些之外没有增加。有人提出，具有较高染色体重排潜力的细胞在低剂量率电离辐射后存活得更好。
