大鼠纹状体富含突触体的部分对甲硫氨酸脑啡肽的摄取。
Met-enkephalin uptake by a synaptosome-enriched fraction of rat striatum.
作者信息
George S R, Van Loon G R
出版信息
Neurosci Lett. 1981 Nov 4;26(3):297-300. doi: 10.1016/0304-3940(81)90148-8.
PMID:7322441
Abstract
We describe the accumulation of tritiated Met-enkephalin by a synaptosome-enriched fraction of rat striatum. Specificity of Met-enkephalin uptake was established by thin layer chromatography. This uptake process is dependent on substrate concentration and is inhibited by excess unlabeled peptide. It requires energy; it is inhibited by coincubation with ouabain.
摘要
我们描述了大鼠纹状体富含突触体的部分对氚标记的甲硫氨酸脑啡肽的摄取。通过薄层色谱法确定了甲硫氨酸脑啡肽摄取的特异性。这种摄取过程依赖于底物浓度，并受到过量未标记肽的抑制。它需要能量；与哇巴因共同孵育可抑制该过程。
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