Rubín A, Krepela K, Janousková A, Biganovská V
Pediatr Radiol. 1981;11(3):125-8. doi: 10.1007/BF00971813.
Sixty-two patients with interstitial lung fibrosis in the age range 2 to 34 years were followed up from 3 to 26 years. The authors stress the important role of an experienced radiologist, who may make a correct diagnosis on the basis of a plain chest radiograph and who plays an important role in follow-up studies because the changing X-ray picture usually corresponds with functional spirometric findings. The diagnosis is established after clinical, radiological and spirometric examinations. Lung biopsy is necessary in atypical cases only. With the diagnosis established treatment with corticosteroids is given in an alternating way and favourable results may be expected in most cases. Six of the female patients have born seven fit children, all without chromosomal aberrations, after five to ten years of corticosteroid treatment.
62例年龄在2至34岁之间的间质性肺纤维化患者接受了3至26年的随访。作者强调经验丰富的放射科医生的重要作用，其可以根据胸部平片做出正确诊断，并且在随访研究中发挥重要作用，因为X线影像的变化通常与肺功能仪检查结果相符。诊断通过临床、放射学和肺功能检查确定。仅在非典型病例中需要进行肺活检。确诊后，以交替方式给予皮质类固醇治疗，大多数情况下可望取得良好效果。6名女性患者在接受皮质类固醇治疗5至10年后生育了7名健康儿童，所有儿童均无染色体异常。
