Arnbjerg J, Andersen S
Nord Vet Med. 1981 Apr-May;33(4-5):199-205.
The herd examined is considered to be a typical representative of Danish pigherds. The investigation shows that acroosteolysis is highly prevalent. As for most pathological conditions in the legs of pigs the condition is concentrated around the bigger of an uneven pair of toes. Frequency and extent of the lesions in the animals are increased with increasing age and with increasing difference in size between the paired toes. Acroosteolysis is caused by vasculitis in the distal vessels followed by osteolysis. During the later development of the condition there is no healing or callus formation in the osteolytic areas, but an extension of the free osseous areas with an apposition of osseous tissue is observed. The clinical manifestations are not specific. The condition is not hereditary, and there are no sex-correlations. The histological appearance is comparable to that of allergic reactions due to e.g. erysipeloid in pigs, and also to allergic acroosteolytic conditions in humans (Raynaud's phenomenon). Therefore, an allergic etiology cannot be rejected.
所检查的猪群被认为是丹麦养猪户的典型代表。调查显示,肢端骨质溶解非常普遍。与猪腿部的大多数病理状况一样,这种情况集中在一对大小不一的脚趾中较大的那个周围。随着动物年龄的增长以及配对脚趾之间大小差异的增加,病变在动物中的发生频率和范围也会增加。肢端骨质溶解是由远端血管的血管炎继而导致骨质溶解引起的。在该病症的后期发展过程中,溶骨区域没有愈合或骨痂形成,但观察到游离骨区域有扩展,并伴有骨组织附着。临床表现并不具有特异性。该病症不具有遗传性,也不存在性别相关性。组织学表现与例如猪丹毒丝菌引起的过敏反应以及人类的过敏性肢端骨质溶解病症(雷诺现象)相似。因此,不能排除过敏病因。