Ekizashvili V K, Rapava E A, Kalandarishvili F A
Tsitologiia. 1981 Nov;23(11):1269-74.
The dynamics of various forms of RNA-polymerases of the rat's brain was studied in the course of postnatal development, using autoradiography and fractionation of enzyme preparation purified from the matrix DNA admixture. In the brain of new-born rats, synthesis of ribosomal RNA proceeds more intensively, with form I enzyme being most active, due to a most active ribosomal RNA synthesis. As the brain develops, by the 12-14 days of life the activity of form I enzyme was found to decrease, whereas that of form II enzyme--to increase.
在出生后的发育过程中，利用放射自显影技术以及从与基质DNA混合物中纯化得到的酶制剂分级分离法，对大鼠大脑中各种形式的RNA聚合酶的动态变化进行了研究。在新生大鼠的大脑中，核糖体RNA的合成更为活跃，由于核糖体RNA合成最为活跃，I型酶最为活跃。随着大脑的发育，在出生后12至14天时，发现I型酶的活性降低，而II型酶的活性增加。
