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[高白血病AKR/J小鼠个体发育中淋巴细胞的细胞学鉴定。生长激素对淋巴器官细胞组成的影响]

[Cytological identification of the lymphocytes in highly leukemic AKR/J mice in ontogenesis. Effect of somatotropin on the cellular composition of the lymphoid organs].

作者信息

Trufakin V A, Chigir' G N, Robinson M V

出版信息

Tsitologiia. 1977 Jul;19(7):821-4.

PMID:73244
Abstract

In AKR/J mice lymphocytes of thymus, spleen and lymph nodes can be classified according to their morphology as revealed by the Stockinger and Kellner staining: I--basophilic cytoplasm, 1--3 large basophilic nucleoli (blast cells), II--basophilic cytoplasm, 1--4 small clearly visible nucleoli (T-lymphocytes), III-weakly basophilic cytoplasm, 1-4 small fairly visible nucleoli (B-lymphocytes). The number of cells of types I and II increases with the progressing of leucaemia. After the administration of somatotrophic hormone the number of cells of types I and II increases only in the lymphoid organs of 5 months old AKR/J mice.

摘要

在AKR/J小鼠中,胸腺、脾脏和淋巴结中的淋巴细胞可根据斯托金格和凯尔纳染色所显示的形态进行分类:I型——嗜碱性细胞质,1 - 3个大的嗜碱性核仁(母细胞);II型——嗜碱性细胞质,1 - 4个清晰可见的小核仁(T淋巴细胞);III型——弱嗜碱性细胞质,1 - 4个相当明显的小核仁(B淋巴细胞)。I型和II型细胞的数量随着白血病的进展而增加。给予生长激素后,I型和II型细胞的数量仅在5月龄AKR/J小鼠的淋巴器官中增加。

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