Jobim L F, Moura N C, Persolli L B, Trachtenberg A, Walford R, Mendes N F
Am J Phys Anthropol. 1981 Nov;56(3):285-90. doi: 10.1002/ajpa.1330560308.
Ninety-nine Tükuna Indians, inhabitants of the high Amazon, were typed for the HLA antigens. The method used was the microlymphocytotoxicity technique recommended by the NIH. At the same time, cross-matching was performed between the lymphocytes of the 99 Indians and the sera of 240 other multiparous Indians. Later the multiparous sera were cross-matched with a selected panel of Caucasoid individuals. The results showed that the most frequent antigens for th HLA-A locus were A2, Aw24 and Aw31. As for the HLA-B locus, B5, Bw39 and B40 were most frequent. The haplotypes HLA-Aw31-Bw39, and A2-B5 were in linkage disequilibrium. The results of the cross-matching showed 21.3% sera with positive reactions against Indian cells. Ten sera presented antibodies against known HLA antigens; five of them were monospecific, four had two specificities, and one showed three specificities. It was not possible to arrive at any conclusion about the 41 remaining sera. Six sera had positive reactions only with Indians cells.
对99名居住在亚马逊上游地区的图库纳印第安人进行了HLA抗原分型。采用的方法是美国国立卫生研究院推荐的微量淋巴细胞毒性技术。同时，对这99名印第安人的淋巴细胞与另外240名经产妇印第安人的血清进行了交叉配型。后来，将经产妇血清与一组选定的高加索人个体进行了交叉配型。结果显示，HLA - A位点最常见的抗原是A2、Aw24和Aw31。至于HLA - B位点，B5、Bw39和B40最为常见。单倍型HLA - Aw31 - Bw39和A2 - B5处于连锁不平衡状态。交叉配型结果显示，21.3%的血清对印第安细胞呈阳性反应。10份血清呈现针对已知HLA抗原的抗体；其中5份为单特异性，4份有两种特异性，1份显示三种特异性。对于其余41份血清无法得出任何结论。6份血清仅与印第安细胞呈阳性反应。
