The behavior of the Nicoladoni-Branham sign at rest and under effort.

The Nicoladoni-Branham sign may change because of exercise. Both dogs with femoral AVF and patients with lower-extremity AVF showed an increase in the Nicoladoni-Branham reaction after exercise as compared with its magnitude at rest. In both groups the AVFs were located near active muscles. We did not find this behavior in 3 patients with AVFs at points distant from the muscles used in exercise.