Saarikoski J, Viluksela M
Arch Environ Contam Toxicol. 1981 Nov;10(6):747-53. doi: 10.1007/BF01054858.
The 96-hr LC50 values of six chloro-, bromo-, and nitro- substituted phenols to the guppy (Poecilia reticulata Peters) were determined by a semistatic method in the pH range of 5 to 8. The pH did not affect appreciably the toxicity of 4-chlorophenol, which is primarily nonionized over the whole range, but the toxicity of more acidic phenols decreased as the pH increased. The changes in toxicity were substantially smaller than they would be, if only the nonionized phenol form were toxic. The results could be explained by assuming that the phenate ion also contributes to the toxicity, but its molar toxicity decreases with rising pH.
采用半静态法在pH值5至8的范围内测定了六种氯代、溴代和硝基取代酚对孔雀鱼（Poecilia reticulata Peters）的96小时半数致死浓度（LC50）值。pH值对4-氯酚的毒性没有明显影响，4-氯酚在整个范围内主要以非离子形式存在，但酸性更强的酚类的毒性随pH值升高而降低。毒性变化比仅非离子化酚形式有毒时要小得多。这些结果可以通过假设酚盐离子也具有毒性来解释，但随着pH值升高其摩尔毒性降低。
