Falconer J, Harvey S, Forbes J M, Scanes C G
Aust J Exp Biol Med Sci. 1981 Oct;59(Pt 5):629-38. doi: 10.1038/icb.1981.56.
Variations to immunoreactive growth hormone (GH) and bioassayable somatomedin-like activity (SLA) were determined in the plasma of the domestic fowl. The plasma concentrations of SLA (potency relative to a pooled serum standard) and GH were both inversely age-related in growing cockerels (Thornber 909) between 3 and 20 weeks of age (SLA, r = 0.454; P less than 0.01, GH, r = 0.548; P less than 0.01) and directly related to each other (r = 0.54; P less than 0.01). In immature birds maintained on a photoperiod of 16 h light, 8 h darkness, plasma concentrations of SLA were highest during the first hour of darkness (1.19 +/- 0.18 units/ ml (u/ml) mean +/- S.E.M., n = 6) and significantly lower 1 h after dawn (0.78 +/- 0.07 u/ml n = 6). No diurnal variations in plasma concentrations of GH were observed. Deprivation of food in two strains of chickens (Thornber 909 and broiler) significantly reduced plasma concentrations of SLA in both strains and increased plasma concentrations of GH in the Thornber strain. Re-feeding fasted Thornber chickens caused the plasma concentrations of SLA and GH to return to normal within 24 h but had no effect in broilers. Deprivation of water, which also reduces food intake, for 12, 18 and 24 h markedly reduced plasma concentrations of SLA but had no effect on plasma GH concentration in Thornber cockerels.
在家禽血浆中测定了免疫反应性生长激素（GH）和生物活性类胰岛素生长因子样活性（SLA）的变化。在3至20周龄的生长公鸡（桑伯909）中，SLA（相对于混合血清标准品的效价）和GH的血浆浓度均与年龄呈负相关（SLA，r = 0.454；P < 0.01，GH，r = 0.548；P < 0.01），且两者呈正相关（r = 0.54；P < 0.01）。在维持16小时光照、8小时黑暗光周期的未成熟鸡中，SLA的血浆浓度在黑暗的第一个小时最高（1.19 ± 0.18单位/毫升（u/ml），平均值±标准误，n = 6），黎明后1小时显著降低（0.78 ± 0.07 u/ml，n = 6）。未观察到GH血浆浓度的昼夜变化。两种品系的鸡（桑伯909和肉鸡）禁食显著降低了两个品系中SLA的血浆浓度，并增加了桑伯品系中GH的血浆浓度。对禁食的桑伯鸡重新喂食使SLA和GH的血浆浓度在24小时内恢复正常，但对肉鸡没有影响。在桑伯公鸡中，缺水12、18和24小时（这也会减少食物摄入）显著降低了SLA的血浆浓度，但对血浆GH浓度没有影响。
