Calatroni A, Bonina L, Focà A, Merendino R
Boll Soc Ital Biol Sper. 1981 Nov 30;57(22):2277-82.
"In vitro" antiviral activity against Picornaviridae and the trials for purification from Str. faecium extract of a factor responsible of these effects are reported. Fractionation on Bio-Gel P-150 and on DEAE-cellulose column and analytical methods for protein and aminosugars were used. Present results demonstrate an antiviral activity of Str. faecium extract against Picornaviridae. Virus inhibiting activity is not correlated with the majority of the Folin reacting proteins, which are present in the bacterial extract. No reliable relationship could be detected for aminosugars containing components, since the amount of aminosugar in fraction from Bio-Gel is extremely low and widely distributed.
报道了粪肠球菌提取物对小核糖核酸病毒科的“体外”抗病毒活性以及从该提取物中纯化负责这些效应的因子的试验。使用了Bio-Gel P-150和DEAE-纤维素柱进行分级分离以及蛋白质和氨基糖的分析方法。目前的结果表明粪肠球菌提取物对小核糖核酸病毒科具有抗病毒活性。病毒抑制活性与细菌提取物中存在的大多数福林反应蛋白无关。对于含氨基糖的成分，未检测到可靠的关系，因为Bio-Gel级分中的氨基糖含量极低且分布广泛。
