通过偏振光吸收光谱法对模型膜中发色团的研究。丁卡因和普鲁卡因的取向与结合。
Studies of chromophores in model membranes by polarized light-absorption spectroscopy. The orientation and binding of tetracaine and procaine.
作者信息
Johansson L B, Lindblom G
出版信息
Biophys J. 1981 Dec;36(3):735-41. doi: 10.1016/S0006-3495(81)84762-5.
Abstract
A method for studying the orientation and binding of chromophores in macroscopically aligned membranes by polarized light absorption spectroscopy is described. Here tetracaine and procaine solubilized in a lamellar phase of octanoyl-1-glyceride (monooctanoin) and water have been investigated. Tetracaine is found to be located in the lipid region with a preferential orientation of the molecular long axis parallel to the hydrocarbon chains. The orientation of procaine, mainly residing in the water region, is very small.
摘要
描述了一种通过偏振光吸收光谱研究发色团在宏观排列膜中的取向和结合的方法。本文研究了溶解在辛酰基-1-甘油（单辛精）和水的层状相中丁卡因和普鲁卡因。发现丁卡因位于脂质区域，分子长轴优先平行于烃链取向。主要存在于水区域的普鲁卡因的取向非常小。
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Studies of chromophores in model membranes by polarized light-absorption spectroscopy. The orientation and binding of tetracaine and procaine.通过偏振光吸收光谱法对模型膜中发色团的研究。丁卡因和普鲁卡因的取向与结合。
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