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淋菌性宫颈炎和淋菌性尿道炎。关于它们的流行病学相关性及沙眼衣原体在其病因学中作用的研究。

Post-gonococcal cervicitis and post-gonococcal urethritis. A study of their epidemiological correlation and the role of Chlamydia trachomatis in their aetiology.

作者信息

Arya O P, Mallinson H, Pareek S S, Goddard A D

出版信息

Br J Vener Dis. 1981 Dec;57(6):395-9. doi: 10.1136/sti.57.6.395.

Abstract

In a study of 157 men and 141 women with gonorrhoea post-gonococcal urethritis (PGU) in men was significantly more common among chlamydia-positive (76%) than among chlamydia-negative (22.5%) patients. Clinical investigations of PGU detected 95% of the patients infected with C trachomatis. PGU was, however, asymptomatic in over half of the patients and a careful follow-up for 3-6 weeks was necessary to detect between 80% and over 90% of cases. PGU was not related to age, past history of gonorrhoea or non-gonococcal urethritis, severity of gonococcal infection, or chlamydial inclusion count. Although post-gonococcal cervicitis (PGC) in women was an identifiable entity, it was detected in only one-third of chlamydia-positive patients. PGC was significantly associated with the 20-29 year-old age group but was not related to symptoms or chlamydial inclusion count. In the absence of facilities for culturing chlamydia, selection on an epidemiological basis of all female consorts of men with PGU, together with the remaining women with PGC, would have resulted in some unnecessary treatments and left untreated up to 30% of those harbouring C trachomatis.

摘要

在一项针对157名男性和141名女性淋病患者的研究中,淋菌性尿道炎后尿道炎(PGU)在男性衣原体阳性患者中(76%)比衣原体阴性患者中(22.5%)更为常见。PGU的临床检查检测出95%的患者感染沙眼衣原体。然而,超过一半的患者PGU无症状,需要进行3至6周的仔细随访才能检测出80%至90%以上的病例。PGU与年龄、既往淋病或非淋菌性尿道炎病史、淋菌感染严重程度或衣原体包涵体计数无关。虽然女性淋菌性宫颈炎(PGC)是一个可识别的实体,但仅在三分之一的衣原体阳性患者中检测到。PGC与20至29岁年龄组显著相关,但与症状或衣原体包涵体计数无关。在没有衣原体培养设施的情况下,基于流行病学选择所有患有PGU男性的女性配偶以及其余患有PGC的女性,会导致一些不必要的治疗,并且使多达30%携带沙眼衣原体的患者得不到治疗。

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