Zander R
Infusionsther Klin Ernahr. 1981 Dec;8(6):274-86.
Beside the necessary volume effect (isoosmotic and isooncotic solution) and the physiological bicarbonate concentration (prevention of dilution acidosis) a possible blood substitute with O2 carrier characteristics should enable an optimal O2 transport: Viscosity as low as possible and shear rate independent (Newtonian behavior), O2 concentration at the given O2 partial pressure at least 6 ml/dl, and mean capillary O2 partial pressure as high as possible. For the judgement of such a blood substitute, the so-called O2 supply index is recommended, i.e., O2 concentration times mean capillary O2 partial pressure divided by viscosity.
除了必要的容量效应（等渗和等胶体渗透压溶液）和生理碳酸氢盐浓度（预防稀释性酸中毒）外，一种具有氧气载体特性的潜在血液替代品应能实现最佳的氧气运输：粘度尽可能低且与剪切速率无关（牛顿流体行为），在给定氧气分压下的氧气浓度至少为6毫升/分升，平均毛细血管氧气分压尽可能高。为了评估这种血液替代品，推荐使用所谓的氧气供应指数，即氧气浓度乘以平均毛细血管氧气分压再除以粘度。
