Schouten T J, Bos J H, Bos C E, van der Pot P J, van den Broek P
Int J Pediatr Otorhinolaryngol. 1981 Dec;3(4):365-9. doi: 10.1016/0165-5876(81)90061-6.
Three patients are described who were treated with levamisole for juvenile laryngeal papillomatosis. In two patients no effect of levamisole was noted during a treatment period of 8-9 months. In the third patient a remission of the disease was noted some months after starting levamisole treatment. In view of our experience with the other two patients the remission may be due to the capricious natural course of the disease rather than to the effect of levamisole. Levamisole does not seem to be an effective drug for the treatment of extensive juvenile papillomatosis and according to the literature not a harmless drug.
本文描述了三名接受左旋咪唑治疗青少年喉乳头状瘤病的患者。两名患者在8 - 9个月的治疗期内未观察到左旋咪唑的疗效。第三名患者在开始左旋咪唑治疗数月后病情出现缓解。鉴于我们对其他两名患者的治疗经验,这种缓解可能是由于该疾病多变的自然病程,而非左旋咪唑的作用。左旋咪唑似乎不是治疗广泛性青少年乳头状瘤病的有效药物,并且根据文献记载,它也并非无害药物。