Banzett R B, Inbar G F, Brown R, Goldman M, Rossier A, Mead J
J Appl Physiol Respir Environ Exerc Physiol. 1981 Sep;51(3):654-9. doi: 10.1152/jappl.1981.51.3.654.
We recorded the diaphragm electromyogram (EMG) of quadriplegic men before and during exposure of the lower torso to continuous negative pressure, which caused shortening of the inspiratory muscles by expanding the respiratory system by one tidal volume. The moving-time-averaged diaphragm EMG was larger during expansion of the respiratory system. When we repeated the experiment with subjects who breathed through a mouthpiece, we found qualitatively similar EMG changes and little or no change in tidal volume or end-tidal CO2 partial pressure. When the pressure was applied or removed rapidly, changes in EMG occurred within one or two breaths. Because end-tidal CO2 partial pressure did not increase, and because the response was rapid, we suggest that the response results from proprioceptive, rather than chemoreceptive, reflexes. As most of these men had complete spinal lesions at C6 or C7 the afferent pathways are likely to be vagal or phrenic.
我们记录了四肢瘫痪男性在其下半身暴露于持续负压之前和期间的膈肌肌电图（EMG），持续负压通过使呼吸系统扩张一个潮气量来导致吸气肌缩短。在呼吸系统扩张期间，移动时间平均膈肌肌电图更大。当我们对通过咬嘴呼吸的受试者重复该实验时，我们发现了定性相似的肌电图变化，并且潮气量或呼气末二氧化碳分压几乎没有变化。当快速施加或去除压力时，肌电图变化在一到两次呼吸内发生。由于呼气末二氧化碳分压没有增加，并且由于反应迅速，我们认为该反应是由本体感受反射而非化学感受反射引起的。由于这些男性中的大多数在C6或C7处有完全性脊髓损伤，传入通路可能是迷走神经或膈神经的。
