Sukhdeo M V, Croll N A
J Parasitol. 1981 Dec;67(6):906-10.
Previous investigators have shown that Trichinella spiralis increases intestinal motility and propulsion. We report here that primary infection with T. spiralis in the mouse increased gut propulsion, measured by the movement of nonabsorbable chromatography beads, on day 5 after infection but not 9 days after infection. Both cortisone acetate, an anti-inflammatory agent, and Lomotil, which reduced gut motility, could suppress the increase in gut propulsion seen 5 days after infection. The results suggest that early inflammation influences peristaltic activity and propulsion of intestinal contents.
先前的研究人员已经表明，旋毛虫会增强肠道蠕动和推进。我们在此报告，小鼠初次感染旋毛虫后，在感染后第5天而非第9天，通过不可吸收的色谱珠移动测量，肠道推进增加。抗炎药醋酸可的松和降低肠道蠕动的洛哌丁胺都可以抑制感染后5天出现的肠道推进增加。结果表明，早期炎症会影响肠道内容物的蠕动活动和推进。
