Thabane Marroon, Marshall John K
Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada.
World J Gastroenterol. 2009 Aug 7;15(29):3591-6. doi: 10.3748/wjg.15.3591.
Post-infectious irritable bowel syndrome (PI-IBS) is a common disorder wherein symptoms of IBS begin after an episode of acute gastroenteritis. Published studies have reported incidence of PI-IBS to range between 5% and 32%. The mechanisms underlying the development of PI-IBS are not fully understood, but are believed to include persistent sub-clinical inflammation, changes in intestinal permeability and alteration of gut flora. Individual studies have suggested that risk factors for PI-IBS include patients' demographics, psychological disorders and the severity of enteric illness. However, PI-IBS remains a diagnosis of exclusion with no specific disease markers and, to date, no definitive therapy exists. The prognosis of PI-IBS appears favorable with spontaneous and gradual resolution of symptoms in most patients.
感染后肠易激综合征（PI-IBS）是一种常见疾病，其肠易激综合征症状在急性肠胃炎发作后出现。已发表的研究报告称，PI-IBS的发病率在5%至32%之间。PI-IBS发生发展的潜在机制尚未完全明确，但据信包括持续性亚临床炎症、肠道通透性改变和肠道菌群变化。个别研究表明，PI-IBS的危险因素包括患者的人口统计学特征、心理障碍和肠道疾病的严重程度。然而，PI-IBS仍然是一种排除性诊断，没有特定的疾病标志物，并且迄今为止，尚无确切的治疗方法。大多数患者的症状会自发且逐渐缓解，PI-IBS的预后似乎良好。
