高牛磺酸和蝇蕈醇模拟牛磺酸和γ-氨基丁酸对肌张力和体温调节的作用。
Homotaurine and muscimol mimic taurine and GABA effects on muscle tone and temperature regulation.
作者信息
Sgaragli G P, Carlà V, Magnani M, Giotti A
出版信息
Naunyn Schmiedebergs Arch Pharmacol. 1978 Nov;305(2):155-8. doi: 10.1007/BF00508286.
PMID:732891
Abstract
Taurine, homotaurine, GABA and muscimol, given intraventricularly to the conscious, unrestrained rabbit cause hypothermia and a reduction in skeletal muscle tone. Taurine and homotaurine desynchronize areas of the motor and limbic cortices, with GABA and muscimol synchronize both tracings and markedly depress the arousal reaction following external stimuli.
摘要
将牛磺酸、高牛磺酸、γ-氨基丁酸（GABA）和蝇蕈醇经脑室注射给清醒、未受束缚的兔子，会导致体温过低并降低骨骼肌张力。牛磺酸和高牛磺酸使运动皮层和边缘皮层区域去同步化，而GABA和蝇蕈醇则使两种记录同步化，并显著抑制外部刺激后的觉醒反应。
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