阿扎丙宗引发的抗惊厥药中毒
Anticonvulsant intoxication precipitated by azapropazone.
作者信息
Roberts C J, Daneshmend T K, Macfarlane D, Dieppe P A
出版信息
Postgrad Med J. 1981 Mar;57(665):191-2. doi: 10.1136/pgmj.57.665.191.
Abstract
A patient is reported who developed a hitherto unrecognized drug interaction between azapropazone and anticonvulsants which led to toxicity with the latter. The mechanism of this interaction is discussed.
摘要
据报道，有一名患者出现了阿扎丙宗与抗惊厥药之间一种此前未被认识到的药物相互作用，这种相互作用导致了抗惊厥药中毒。本文讨论了这种相互作用的机制。
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本文引用的文献
1
Effect of single doses of sodium valproate on serum phenytoin levels and protein binding in epileptic patients.
Clin Pharmacol Ther. 1980 Jan;27(1):89-95. doi: 10.1038/clpt.1980.14.
2
The pharmacology and pharmacokinetics of azapropazone - a review.阿扎丙宗的药理学与药代动力学——综述
Curr Med Res Opin. 1976;4(1):3-16. doi: 10.1185/03007997609109277.
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