Arakawa A, Baba E, Fukata T
Poult Sci. 1981 Oct;60(10):2203-9. doi: 10.3382/ps.0602203.
Three experiments were conducted to investigate the effects of concurrent infections of Salmonella typhimurium and Eimeria tenella on establishment of salmonella infection in chickens. There were four groups in all experiments: noninfected controls, birds infected with 50,000 E. tenella oocysts, birds infected with approximately 10(4) S. typhimurium, and birds infected with a combination of E. tenella S. typhimurium. In the first experiment with three identical trials of 80 birds each, chickens were infected with the organisms and necropsied 1, 3, 5, and 7 days later. Concurrent infections of coccidia and salmonella did not significantly enhance salmonella infection in terms of number of salmonella in the ceca and the number of positive birds for salmonella. In the second experiment, consisting of three replications of 80 chickens each, birds were exposed to salmonella on the day of coccidia exposure, 2, 4, or 6 days thereafter, and killed 1 day late. Salmonella in the ceca of coccidia-infected chickens did not increase significantly as compared with salmonella exposure alone. In the third experiment, with three replication of 60 birds each, chickens were exposed consecutively to salmonella 1 through 5 days and killed 7, 10, and 14 days after coccidia infection. There was a significant increase in number of salmonella in coccidia-infected ceca and number of chickens positive for salmonella in ceca or in liver when compared with those of salmonella infection alone.
进行了三项实验，以研究鼠伤寒沙门氏菌和柔嫩艾美耳球虫同时感染对鸡沙门氏菌感染定植的影响。所有实验均分为四组：未感染对照组、感染50,000个柔嫩艾美耳球虫卵囊的鸡、感染约10⁴个鼠伤寒沙门氏菌的鸡，以及同时感染柔嫩艾美耳球虫和鼠伤寒沙门氏菌的鸡。在第一个实验中，进行了三次相同的试验，每次试验有80只鸡，给鸡感染这些病原体，然后在1、3、5和7天后进行剖检。就盲肠中沙门氏菌的数量和沙门氏菌检测呈阳性的鸡只数量而言，球虫病和沙门氏菌的同时感染并未显著增强沙门氏菌感染。在第二个实验中，由三次重复组成，每次有80只鸡，在感染球虫的当天、之后2、4或6天让鸡接触沙门氏菌，并在1天后宰杀。与仅接触沙门氏菌相比，感染球虫的鸡盲肠中的沙门氏菌数量没有显著增加。在第三个实验中，进行了三次重复，每次有60只鸡，鸡在第1至5天连续接触沙门氏菌，并在感染球虫后7、10和14天宰杀。与仅感染沙门氏菌的情况相比，感染球虫的盲肠中沙门氏菌数量以及盲肠或肝脏中沙门氏菌检测呈阳性的鸡只数量显著增加。
