Schohn D C, Klein S, Mitsuishi Y, Jahn H A
Proc Eur Dial Transplant Assoc. 1981;18:160-8.
Acetate in dialysis fluid induces during haemodialysis a fall in systemic vascular resistance. In patients with hepatic insufficiency, acetate concentrations are higher than in patients without hepatic insufficiency and in such patients vascular sensitivity to acetate is perhaps potentiated by modifications of acid base status. The close inverse correlations between acetate concentrations and systemic vascular resistance are strong indications that acetate is a major factor involved in the genesis of 'dialysis hypotension'.
透析液中的醋酸盐在血液透析过程中会导致全身血管阻力下降。在肝功能不全的患者中，醋酸盐浓度高于无肝功能不全的患者，并且在这类患者中，酸碱状态的改变可能会增强血管对醋酸盐的敏感性。醋酸盐浓度与全身血管阻力之间紧密的负相关有力地表明，醋酸盐是导致“透析性低血压”发生的主要因素。
