Vangelista A, Frascá G, Biagini G, Bonomini V
Proc Eur Dial Transplant Assoc. 1981;18:503-7.
Twenty-six cases of Mesangial Proliferative Glomerulonephritis and diffuse IgM deposits were studied. Nine had nephrotic syndrome; 8 minimal urinary abnormalities; 7 asymptomatic proteinuria; 2 recurrent haematuria. Immunofluorescence revealed granular mesangial deposits in 14 cases and interrupted linear deposits in the others, chiefly along the capillary walls. In the latter group the clinical picture was mainly nephrotic syndrome or asymptomatic proteinuria. The clinical course is favourable: 7 cases recovered; 12 improved; 7 did not show any change. No progression of renal lesions was observed. Despite uniform histological features, this nephropathy is unlikely to be a unique disease, but in our opinion it should be considered separately from other glomerulopathies.
对26例系膜增生性肾小球肾炎伴弥漫性IgM沉积进行了研究。9例有肾病综合征；8例有轻微尿液异常；7例有无症状蛋白尿；2例有复发性血尿。免疫荧光显示14例有颗粒状系膜沉积，其他病例有间断的线性沉积，主要沿毛细血管壁分布。后一组的临床表现主要为肾病综合征或无症状蛋白尿。临床病程良好：7例恢复；12例好转；7例无变化。未观察到肾脏病变进展。尽管组织学特征一致，但这种肾病不太可能是一种独特的疾病，但我们认为应将其与其他肾小球病分开考虑。
