Steiger H J
Surg Neurol. 1981 Dec;16(6):459-61. doi: 10.1016/0090-3019(81)90247-0.
Repeated Doppler sonograms were performed on the common carotid arteries of patients with severe brain injury. The evolution of the flow-wave shape in 9 patients who developed massive intracranial hypertension and finally died with cerebral circulatory arrest demonstrated that, with increasing peripheral vascular resistance, the diastolic flow diminished while the peak systolic flow was not significantly affected. Thus, the so-called pulsatility index, a measure of the pulsatile characteristic of the sonogram, can be used as a semiquantitative measure of intracranial perfusion. Measurements on healthy control subjects provided pulsatility indexes between 1.5 and 2.0. In cases of posttraumatic brain edema, these values increased gradually. These data suggest that values higher than 3 are associated with severe intracranial hypertension and the decerebrate state. In angiographically demonstrated cerebral circulatory arrest, the pulsatility index was found to range between 6 and 8.
对重度脑损伤患者的颈总动脉进行了多次多普勒超声检查。对9例发生严重颅内高压并最终死于脑循环停止的患者的血流波形演变进行观察，结果显示，随着外周血管阻力增加，舒张期血流减少，而收缩期峰值血流未受到显著影响。因此，所谓的搏动指数，作为超声图搏动特征的一种度量，可以用作颅内灌注的半定量指标。对健康对照者的测量结果显示搏动指数在1.5至2.0之间。在创伤后脑水肿的情况下，这些值会逐渐升高。这些数据表明，高于3的值与严重颅内高压和去大脑状态相关。在血管造影显示脑循环停止的病例中，发现搏动指数在6至8之间。
