Maltoni C, Lodi P
Environ Health Perspect. 1981 Oct;41:85-8. doi: 10.1289/ehp.814185.
The results of systematic cytological sputum examinations of 3,380 Italian VC-PVC industry workers and of 2,287 workers in other industries at different potential risk and chosen as control groups are reported. The results indicate an increase in cellular abnormalities and dysplasias in the epithelium of the respiratory tract among VC-PVC workers. These data are in line with experimental results showing that VC produces lung tumors in mice and with early epidemiological evidence among exposed workers.
报告了对3380名意大利氯乙烯-聚氯乙烯(VC-PVC)行业工人以及2287名处于不同潜在风险且被选为对照组的其他行业工人进行系统痰细胞学检查的结果。结果表明,VC-PVC行业工人呼吸道上皮细胞异常和发育异常有所增加。这些数据与表明氯乙烯在小鼠中诱发肺癌的实验结果以及接触工人中的早期流行病学证据一致。