对变形链球菌进行免疫球蛋白G Fc反应性检测。
Examination of Streptococcus mutans for immunoglobulin G Fc reactivity.
作者信息
Shea C, Ferretti J J
出版信息
Infect Immun. 1981 Dec;34(3):851-5. doi: 10.1128/iai.34.3.851-855.1981.
Abstract
Representative strains of oral streptococci were tested for Fc immunoglobulin G (IgG) reactivity by two different techniques, agglutination of rabbit-IgG sensitized sheep erythrocytes and uptake of human and rabbit 125I-radiolabeled IgG. None of the S. mutans serotypes a through e reacted with the Fc region of either human or rabbit IgG. Additionally, other streptococci such as S. sanguis, S. salivarius, S. faecalis, and S. mitis failed to show appreciable Fc reactivity as assayed by these techniques. The group A, C, and G streptococci, previously shown to possess Fc reactivity, proved to be reactive in these experiments, as did a protein A-containing strain of Staphylococcus aureus.
摘要
通过两种不同技术对口腔链球菌的代表性菌株进行了Fc免疫球蛋白G（IgG）反应性测试，即兔IgG致敏绵羊红细胞的凝集反应以及人和兔125I放射性标记IgG的摄取。变形链球菌a至e血清型均未与人或兔IgG的Fc区域发生反应。此外，通过这些技术检测，其他链球菌如血链球菌、唾液链球菌、粪链球菌和缓症链球菌未表现出明显的Fc反应性。先前已证明具有Fc反应性的A、C和G组链球菌在这些实验中被证明具有反应性，含蛋白A的金黄色葡萄球菌菌株也具有反应性。
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