Hicks W G, Kennedy T J, Keister D M, Miller M L
J Dairy Sci. 1981 Nov;64(11):2266-9. doi: 10.3168/jds.S0022-0302(81)82840-8.
Efficacy of a teat dip containing .5% chlorhexidine digluconate and 6% glycerin was tested on 46 clinically normal cows, each with functional quarters. Twice daily immediately after milking, all teats were exposed to a suspension containing 5 X 10(7) colony forming units of Staphylococcus aureus. After each exposure to the infective broth, the left teats were dipped in teat dip while the right teats remained as untreated controls. The study continued until sufficient number of infections occurred to establish efficacy. Mastitis screening followed standard procedures as established by the National Mastitis Council and identified 24 infected teats in the control group and 6 in the treated group for 75% efficacy. The tested teat dip was effective in reducing the incidence of intramammary infections caused by Staphylococcus aureus under experimental exposure. No chapping or irritation occurred with use of the teat dip.
对46头临床健康且每个乳腺区功能正常的奶牛，测试了一种含有0.5%葡萄糖酸洗必泰和6%甘油的乳头浸液的效果。每天挤奶后立即进行两次，所有乳头都接触含有5×10⁷金黄色葡萄球菌菌落形成单位的悬液。每次接触感染性肉汤后，左乳头浸在乳头浸液中，而右乳头作为未处理的对照。该研究持续进行，直到发生足够数量的感染以确定疗效。乳腺炎筛查遵循美国国家乳腺炎委员会制定的标准程序，对照组中有24个感染乳头，治疗组中有6个感染乳头，有效率为75%。在实验暴露条件下，测试的乳头浸液能有效降低由金黄色葡萄球菌引起的乳房内感染的发生率。使用乳头浸液未出现皲裂或刺激现象。
