Sejean S, Turpin J C, Quarre M C, Tournaire M
J Gynecol Obstet Biol Reprod (Paris). 1981;10(7):699-709.
It is necessary to think about the frequency of mistakes made at term as well as about the rare case of antenatal microcephaly when confronted with an abnormally small biparietal diameter. The authors, when confronted on twelve occasions with the problem of antenatal microcephaly, classified two situations: the discovery from systematic screening of a break in the growth of the cranial diameters. In the case of overall growth retardation of the fetus it becomes necessary to carryout amniocentesis to look for associated chromosome abnormality (two out of twelve cases); ultrasound monitoring of a pregnancy in the woman who has previously delivered a microcephalic infant in order to diagnose a possible recurrence of the condition (three out of the twelve cases). Furthermore the authors point out tha there are limits to the method. Ultrasound is only a complementary examination and the results obtained should be studied critically, confirmed by repeated examinations and integrate into the whole clinical picture. Finally, it is not always possible to differentiate between the normal and the abnormal by ultrasound. In borderline cases ultrasound has the advantage that it can point out the need for extra careful post-natal examination of the infant.
当遇到双顶径异常小时,有必要考虑足月时出现错误的频率以及产前小头畸形这种罕见情况。作者在12次遇到产前小头畸形问题时,将情况分为两类:通过系统筛查发现颅骨直径生长中断。在胎儿整体生长迟缓的情况下,有必要进行羊膜穿刺术以寻找相关的染色体异常(12例中有2例);对先前分娩过小头畸形婴儿的女性进行孕期超声监测,以诊断该病可能的复发情况(12例中有3例)。此外,作者指出该方法存在局限性。超声只是一种辅助检查,所获得的结果应审慎研究,通过反复检查加以证实,并纳入整个临床情况中。最后,超声并不总是能够区分正常与异常情况。在临界病例中,超声的优势在于它能够指出需要对婴儿进行格外仔细的产后检查。