Buzelin J M
J Urol (Paris). 1981;87(9):561-86.
Approaching the currently widely studied field of the pathology of vesical inhibition, the authors review the symptomatology and consequences of vesical hyperreflectivity. They begin with clinical definitions of frequency and urgency and then attempt to draw out the limits of the clinical picture involved in incontinence because of urgency (ineffective contraction of the striate sphincter, impossibility of inhibition of vesical contraction, sudden loss of urethral tone as a result of urethral instability), and that of reflex incontinence, true enuresis. They then describe the various cystometric aspects of such forms of vesical instability, finishing with an area about which there is still little knowledge but certainly fundamental: development of bladder hypertrophy and the possible explanation of infectious complications or even vesico-ureteric reflux by simple vesical hyperreflectivity. In fact, each occlusion of the sphincter system in the presence of sudden increased vesical contraction of a non-inhibited bladder provokes a minor episode of transient complete vesical retention. Accumulation of such accidents results in severe bladder hypertrophy with increased tone. Trabeculation, diverticulation, aggravation of infection and the development of para-urethral diverticula responsible for reflux underline the grave nature of the problems affecting certain patients with vesical hyper-reflectivity. This occurs even in the absence of dyssynergism and in the absence of typical neurological disturbances. There is thus the possibility of a neurogenic bladder and the consequences of a neurogenic bladder without necessarily any organic cervico-urethral obstruction.
在探讨目前广泛研究的膀胱抑制病理学领域时,作者回顾了膀胱反射亢进的症状学及后果。他们首先阐述了尿频和尿急的临床定义,接着试图明确因尿急导致的尿失禁(尿道括约肌无效收缩、无法抑制膀胱收缩、尿道不稳定导致尿道张力突然丧失)以及反射性尿失禁(真性遗尿)所涉及临床表现的界限。然后,他们描述了此类膀胱不稳定形式的各种膀胱测压表现,最后论述了一个仍知之甚少但肯定至关重要的领域:膀胱肥大的发展以及单纯膀胱反射亢进对感染并发症甚至膀胱输尿管反流的可能解释。事实上,在非抑制性膀胱突然出现膀胱收缩增强的情况下,括约肌系统的每次梗阻都会引发一次短暂的完全性膀胱潴留小发作。此类情况的累积会导致严重的膀胱肥大及张力增加。小梁形成、憩室形成、感染加重以及导致反流的尿道旁憩室的发展突显了影响某些膀胱反射亢进患者问题的严重性。即使在没有协同失调和典型神经功能障碍的情况下也会发生这种情况。因此,有可能存在神经源性膀胱以及神经源性膀胱的后果,而不一定存在任何器质性宫颈 - 尿道梗阻。