Williams J P
J Embryol Exp Morphol. 1981 Oct;65 Suppl:89-101.
Catch-up growth, defined as growth velocity above the statistical limits of normality for age or maturity during a defined period of time, is distinguished from compensatory growth since it makes up for a potential loss rather than an actual loss and is seen in the whole body as opposed to specific organs. The cellular explanation for catch-up based on the work of Winick is described and a recent challenge to this explanation is briefly discussed. The mechanism of mismatch between actual size and 'planned' size suggested by Tanner is described and tested. In a series of experiments conducted in rats of different ages the degree of mismatch and the role of catch-up are compared for two different parameters, body weight and nose-rump length. It was found that the two parameters behaved differently and it is suggested that while the concept of mismatch is still acceptable the idea of a single central mechanism is not supported. It is suggested that the mismatch mechanism is a cellular phenomenon.
追赶生长被定义为在一段特定时间内，生长速度高于同年龄或成熟度的正常统计范围，它与代偿性生长不同，因为它弥补的是潜在损失而非实际损失，且是全身出现这种情况，而非特定器官。文中描述了基于维尼克研究成果的关于追赶生长的细胞层面解释，并简要讨论了近期对这一解释的挑战。文中阐述并验证了坦纳提出的实际大小与“计划”大小不匹配的机制。在针对不同年龄大鼠进行的一系列实验中，对体重和鼻臀长这两个不同参数的不匹配程度及追赶生长的作用进行了比较。结果发现这两个参数表现各异，这表明虽然不匹配的概念仍然可行，但单一核心机制的观点并未得到支持。有人提出不匹配机制是一种细胞现象。
